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H+ + meso-diaminopimelate → L-lysine + CO2 (R367)
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L-homoserine + ATP → O-phospho-L-homoserine + H+ + ADP (R153)
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L-homoserine + succinyl-CoA → coenzyme A + O-succinyl-L-homoserine (R369)
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NAD+ + (R)-lactate ← NADH + pyruvate + H+ (R504)
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ethanol + NAD+ ↔ acetaldehyde + NADH + H+ (R157)
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coenzyme A + acetaldehyde + NAD+ ↔ NADH + H+ + acetyl-CoA (R156)
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formate + acetyl-CoA ↔ coenzyme A + pyruvate (R278)
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L-aspartate + ATP → L-aspartyl-4-phosphate + ADP (R295)
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Overexpression
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Feedback insensitive
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H+ + L-homoserine → H+ + L-homoserine (R00818)
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phosphoenolpyruvate + β-D-glucopyranose → β-D-glucose 6-phosphate + pyruvate (R4216)
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D-Glucose + H+ → D-Glucose + H+ (R00800)
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phosphate + oxaloacetate ↔ phosphoenolpyruvate + hydrogencarbonate (R390)
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L-aspartate ↔ ammonium + fumarate (R1558)
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ATP + D-Glucose → ADP + D-glucopyranose 6-phosphate + H+ (R00472)
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L-aspartate 4-semialdehyde + NADP+ + phosphate ↔ L-aspartyl-4-phosphate + NADPH + H+ (R236)
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L-homoserine + NAD(P)+ ← L-aspartate 4-semialdehyde + NAD(P)H + H+ (R234)
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Overexpression
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Feedback insensitive
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L-glutamate + NADP+ ← NADPH + 2-oxoglutarate + H+ + L-glutamine (R553)
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3-phospho-D-glycerate + ATP ↔ 3-phospho-D-glyceroyl-phosphate + ADP (R655)
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H2O + adenosine + H+ → inosine + ammonium (R1082)
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H2O + AMP → aldehydo-D-ribose 5-phosphate + adenine (R3061)
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adenosine + ATP → H+ + ADP + AMP (R2254)
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2-oxoglutarate + L-aspartate ↔ L-glutamate + oxaloacetate (R734)
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coenzyme A + 2-oxoglutarate + NAD+ → NADH + succinyl-CoA + CO2 (R1038)
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pyruvate + ATP ↔ phosphoenolpyruvate + H+ + ADP (R345)
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pyruvate + GTP ← phosphoenolpyruvate + H+ + GDP (R1153)
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H+ + phosphoenolpyruvate + UDP → pyruvate + UTP (R00861)
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phosphoenolpyruvate + CDP + H+ → pyruvate + CTP (R00862)
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phosphoenolpyruvate + dTDP + H+ → pyruvate + dTTP (R00863)
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H2O + O-phospho-L-homoserine → L-threonine + phosphate (R646)
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H2O + acetyl-CoA + oxaloacetate → coenzyme A + H+ + citrate (R92)
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L-homoserine + H+ → L-homoserine + H+ (R00837)