Escherichia coli HGA1
Strain derived from a randomly mutated strain.
Ancestors
Derived strains
- Escherichia coli HGB1
- Escherichia coli HGB2
- Escherichia coli HGB3
- Escherichia coli HGB4
- Escherichia coli HGB5
- Escherichia coli HGB6
Genotype with respect to parental
ΔtyrR, pheA and trpE
Genotype with respect to wild type
F+ (λ) | l-Tyrosine auxotrophic | ΔtyrR, pheA and trpE | Plasmid pAP11 addedBars (|) indicate differences between strains.
Plasmids
-
pAP11 (pAP with aroGfbr, tyrAfbr, tktA and ppsA, p15A ori with PRPL)
Modifications
| Origin | Gene | Organism | Modification |
|---|---|---|---|
|
Silencing
|
|||
|
Silencing
|
|||
|
Silencing
|
|||
|
Feedback insensitive
|
|||
|
Feedback insensitive
|
|||
|
Overexpression
|
|||
|
Overexpression
|
Production
| Metabolites | Production type | Production | Biomass | Carbon source | Time | Scale | Ref. |
|---|---|---|---|---|---|---|---|
| L-tyrosine | Titer | 4.22 g/L | 48 h * | Flask | [268] |
* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.